#Snapgene adaptors full#

See citations in PubMed for homologs of this gene provided by HomoloGene P62 Links the Autophagy Pathway and the Ubiquitin-Proteasome System in Endothelial Cells during Atherosclerosis.The Ubiquitin Sensor and Adaptor Protein p62 Mediates Signal Transduction of a Viral Oncogenic Pathway.Lnc-MEG3 inhibits invasion, migration, and epithelial- mesenchymal transition of nasopharyngeal carcinoma cells by regulating sequestosome 1.

The Autophagy Cargo Receptor SQSTM1 Inhibits Infectious Bursal Disease Virus Infection through Selective Autophagic Degradation of Double-Stranded Viral RNA.High expression of p62/SQSTM1 predicts shorter survival for patients with pancreatic cancer.Expression Ubiquitous expression in thyroid (RPKM 57.3), gall bladder (RPKM 54.3) and 25 other tissues See more Orthologs mouse all NEW Try the new Gene table Mutations in this gene result in sporadic and familial Paget disease of bone. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals.

#Snapgene adaptors full#

Full Name sequestosome 1 provided by HGNC Primary source HGNC:HGNC:11280 See related Ensembl:ENSG00000161011 MIM:601530 AllianceGenome:HGNC:11280 Gene type protein coding RefSeq status REVIEWED Organism Homo sapiens Lineage Eukaryota Metazoa Chordata Craniata Vertebrata Euteleostomi Mammalia Eutheria Euarchontoglires Primates Haplorrhini Catarrhini Hominidae Homo Also known as p60 p62 A170 DMRV OSIL PDB3 ZIP3 p62B NADGP FTDALS3 Summary This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway.